QUIC is the name for a new experimental protocol, and it stands for Quick UDP Internet Connection. The protocol supports a set multiplexed connections over UDP and was designed to provide security protection equivalent to TLS/SSL, along with reduced connection and transport latency found in TCP connections. An experimental implementation is being put in place in Chrome by a team of engineers at Google but also be found in Opera 16+ now.
To check if you have QUIC enabled or disabled you need to open a new tab in Chrome and go to chrome://flags/
Once at this page you should be able to scroll down and find Experimental QUIC protocol.
Why may you want to disable QUIC?
If you are using any web proxy or web filtering solution normally they will record and analyse TCP traffic is that is on port 80 and 443 but because QUIC uses UDP on port 80 and 443 this traffic can go through unfiltered and unmonitored. If you are finding your web proxy or web filtering is allowing some sites are should be blocked normally. Google services such as YouTube and Google Drive make use of QUIC for streaming media and serving web pages. Adoption rates are low currently but Google is pushing for higher adoption as part of the HTTP2 revision.